Longevity & Cellular
Oxidative Stress Studies
Quantity
Ships from the United States with tracking · free shipping over $200
Certificates of analysis
Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.
Authenticity
Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.
Verify a batch →Independently tested
Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.
A certificate for your lot
The report that ships with your order describes the batch you received — not the product line, and not a representative sample.
COA-backed replacement
If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.
Tracked dispatch
Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.
About this compound
C₁₀H₁₇N₃O₆S
Glutathione is a tripeptide and the most abundant intracellular antioxidant in mammalian cells. It cycles between reduced and oxidised forms, and the ratio between them is used across the literature as a working index of cellular oxidative state — which is why it appears as a measurement as often as a subject.
Full specification
How it works
The pathways L-Glutathione acts on, and what each one does. Signalling described from preclinical models.
Free Radical Scavenging
The free thiol group donates electrons directly to reactive species, which is how it acts as an antioxidant without requiring an enzyme to mediate.
GPx & GST Catalysis
It is also the substrate for glutathione peroxidase and S-transferase — enzymes that cannot function without it. That makes the tripeptide a cofactor as much as a scavenger.
Cellular Redox Homeostasis
The ratio of reduced to oxidised glutathione is used across the literature as a working index of cellular redox state, which is why the molecule appears as a measurement as often as a subject.
Uses & applications
The main areas under study, and the study-reported figures behind them.
The reduced-to-oxidised ratio serves as the working index of cellular oxidative state across this literature.
Frontiers Pharmacol. 2014
Depletion is a defining step in ferroptosis, which makes the tripeptide central to that field rather than incidental to it.
Cell Death & Disease 2023
Nrf2 governs the transcription of the enzymes that synthesise and use it, so the pathway and the molecule regulate each other.
Lee et al. 2019
Conjugation by S-transferases is the mechanism, with xenobiotic clearance measured as the outcome.
Rai R. 2021
What the published work measures
The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.
Molecular structure
The deposited three-dimensional conformer for this compound, paired with its verified reference values.
Drag to rotate
37 atoms
37 atoms, 36 bonds, C10H17N3O6S. Deposited conformer from PubChem CID 124886, not a drawing.
C₁₀H₁₇N₃O₆S
Third-party verified
Every batch of L-Glutathione is sent to an accredited independent laboratory before it ships. Here is what we screen for.
Quantifies purity and reports it on the lot certificate
Verifies the exact molecular identity
Lead, arsenic, cadmium & mercury
Bacterial endotoxin levels
No microbial contamination
Actual peptide mass per vial verified
FAQ
Glutathione is a tripeptide and the most abundant intracellular antioxidant in mammalian cells. It cycles between reduced and oxidised forms, and the ratio between them is used across the literature as a working index of cellular oxidative state — which is why it appears as a measurement as often as a subject.
Published research on L-Glutathione concentrates on Oxidative Stress & Antioxidant Defense, Ferroptosis & Lipid Peroxidation, Nrf2/HO-1 Pathway Signaling and Detoxification & Redox Defense. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.
The literature describes L-Glutathione acting across Free Radical Scavenging, GPx & GST Catalysis and Cellular Redox Homeostasis, reported respectively as Direct Antioxidant, Enzyme Cofactor and Redox & Detox. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.
L-Glutathione has a molecular formula of C₁₀H₁₇N₃O₆S, an average mass of 307.32 g/mol and the sequence γ-L-Glutamyl-L-Cysteinyl-Glycine. It is indexed under CAS 70-18-8. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.
Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. L-Glutathione is water-soluble; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.
No. L-Glutathione is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.
Cited sources
Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.
For research use only
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
Before you order
Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.
