Longevity & Cellular
Mitochondrial Function Studies
Quantity
Ships from the United States with tracking · free shipping over $200
Certificates of analysis
Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.
Authenticity
Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.
Verify a batch →Independently tested
Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.
A certificate for your lot
The report that ships with your order describes the batch you received — not the product line, and not a representative sample.
COA-backed replacement
If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.
Tracked dispatch
Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.
About this compound
C32H49N9O5
SS-31, also called elamipretide, is a four-residue peptide that concentrates at the inner mitochondrial membrane. It does not bind a receptor; it associates with cardiolipin, a phospholipid specific to that membrane and central to its structural integrity. Research examines mitochondrial function and cristae architecture.
Full specification
How it works
The pathways SS-31 acts on, and what each one does. Signalling described from preclinical models.
Inner Mitochondrial Membrane Stabilization
Rather than binding a receptor it associates with cardiolipin, a phospholipid found only in the inner mitochondrial membrane and central to its structure. That specificity is what concentrates it there.
Mitochondrial Reactive Oxygen Species Reduction
Stabilising cristae architecture is reported to reduce electron leak — the proposed route to lowering ROS production at source rather than scavenging it afterwards.
Bioenergetic Function Restoration
ATP synthesis is measured in models of mitochondrial dysfunction, where the question is whether structural stabilisation translates into recovered output.
Uses & applications
The main areas under study, and the study-reported figures behind them.
Cardiac mitochondria are unusually dense, which is why heart failure models feature so heavily for a cardiolipin-binding compound.
Daubert MA et al. 2017
Reperfusion generates a burst of reactive oxygen species, making it a direct test of the proposed mechanism.
Zhao K et al. 2007
Cristae architecture and bioenergetic output are measured in aged tissue against younger controls.
Siegel MP et al. 2013
Renal tubular cells are also mitochondria-rich, and the endpoints mirror the cardiac work.
Birk AV et al. 2013
What the published work measures
The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.
Molecular structure
A computed low-energy conformer built from this compound's published connectivity and stereochemistry, paired with its verified reference values.
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95 atoms
95 atoms, 96 bonds, C32H49N9O5. Connectivity and stereochemistry from PubChem CID 11764719. The arrangement is one computed low-energy conformer, not a measured structure — a flexible peptide adopts many conformations in solution.
C32H49N9O5
Third-party verified
Every batch of SS-31 is sent to an accredited independent laboratory before it ships. Here is what we screen for.
Quantifies purity and reports it on the lot certificate
Verifies the exact molecular identity
Lead, arsenic, cadmium & mercury
Bacterial endotoxin levels
No microbial contamination
Actual peptide mass per vial verified
FAQ
SS-31, also called elamipretide, is a four-residue peptide that concentrates at the inner mitochondrial membrane. It does not bind a receptor; it associates with cardiolipin, a phospholipid specific to that membrane and central to its structural integrity. Research examines mitochondrial function and cristae architecture.
Published research on SS-31 concentrates on Heart Failure, Reperfusion Injury, Mitochondrial Aging and Renal Protection. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.
The literature describes SS-31 acting across Inner Mitochondrial Membrane Stabilization, Mitochondrial Reactive Oxygen Species Reduction and Bioenergetic Function Restoration, reported respectively as Cardiolipin Binding, ROS Scavenging and ATP Synthesis. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.
SS-31 has a molecular formula of C32H49N9O5, an average mass of 638.8 g/mol and the sequence D-Arg-Dmt-Lys-Phe-NH2. It is indexed under CAS Elamipretide, MTP-131, Bendavia. It ships as lyophilized powder (5mg). Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.
Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. SS-31 is soluble in water; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.
No. SS-31 is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.
Cited sources
Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.
For research use only
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
Before you order
Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.
