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Routine Peptides
HPLC tested
Representative HPLCPer lot
Selank research vial

Cognitive & Nootropic

Selank

Stress Response Studies

Third-party testedCOA per lotView COA · 99.607%
$7210mg · $7.20/mg

Quantity

1

Ships from the United States with tracking · free shipping over $200

PassedSterility & Endotoxins
PassedNet Content & Purity
Research use only
Third-party tested
COA with every lot
Tracked shipping

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Semax

10mg

$72.00

Authenticity

Every vial carries a code

Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.

Verify a batch →

Verified, lot by lot

Per lot
  • Independently tested

    Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.

  • A certificate for your lot

    The report that ships with your order describes the batch you received — not the product line, and not a representative sample.

  • COA-backed replacement

    If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.

  • Tracked dispatch

    Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.

🔬
40+
Published Studies
Anxiolytic & nootropic research
🧬
7
Amino Acids
Tuftsin-derived heptapeptide
🎯
4
Research Areas
Anxiolytic Mechanisms · Memory & Learning · Cytokine & Immune Modulation & more

About this compound

What Selank is

C33H57N11O9

Selank is a seven-residue peptide built on tuftsin, a naturally occurring immune peptide, with the same stabilising tripeptide tail used in Semax. Research examines anxiolytic and stress-response endpoints, and much of the primary work sits alongside Semax in the same Russian research literature.

Formula
C33H57N11O9
Molecular weight
751.88 g/mol
Form
Lyophilized powder
CAS / ID
129954-34-3
Read the full Selank research monograph →

Full specification

Sequence
H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH
Molecular weight
751.88 g/mol
Molecular formula
C33H57N11O9
Physical form
Lyophilized powder
Documented purity
Quantified by HPLC, reported per lot
Storage
-20°C for long-term stability
Solubility
Water or bacteriostatic water

How it works

How Selank works

The pathways Selank acts on, and what each one does. Signalling described from preclinical models.

GABA-A Receptor Modulation

GABAergic

Anxiolytic endpoints are attributed to modulation of GABA-A signalling, though the peptide is not a classical benzodiazepine-site ligand and the interaction is described as indirect.

  • Modulates GABA-A subunit expression
  • Anxiolytic without benzodiazepine-type sedation
  • No physical dependence reported preclinically

BDNF & Enkephalin Upregulation

Neurotrophin

Reported increases in BDNF expression and in enkephalin stability connect the peptide to neurotrophic and opioid-adjacent signalling in the same models.

  • BDNF expression raised in hippocampal regions
  • Stabilises enkephalin by inhibiting enkephalinase
  • Serotonin and dopamine turnover modulated

Tuftsin-Derived Immune Regulation

Immunomodulatory

The sequence is built on tuftsin, a naturally occurring immune peptide — which is why immunomodulatory endpoints appear in a literature otherwise concerned with anxiety.

  • Built on tuftsin, a natural immunomodulator
  • Pro-inflammatory cytokine expression modulated
  • Interferon alpha and gamma signalling affected

Uses & applications

What Selank is researched for

The main areas under study, and the study-reported figures behind them.

Neuropharmacology

Anxiolytic Mechanisms

Anxiety-like behavior is measured in standard rodent paradigms, with GABAergic modulation proposed rather than demonstrated.

Semenova et al. 2010

Cognitive Research

Memory & Learning

Cognitive endpoints are measured alongside the anxiolytic ones, usually within the same protocol.

Kozlovskaya et al. 2008

Immunology

Cytokine & Immune Modulation

Immune endpoints follow from the tuftsin origin and sit oddly alongside an otherwise behavioral literature.

Zozulya et al. 2012

Gene Expression

Transcriptomic Studies

Gene-expression profiling has been used to look for a mechanism the behavioral work could not pin down.

Inozemtseva et al. 2009

What the published work measures

The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.

  • Anxiety Reduction (Preclinical Models)
  • BDNF Expression Increase
  • Cognitive Performance (Memory Tasks)
  • Cytokine Modulation (IL-6, TNF-α)

Molecular structure

The Selank molecule

A computed low-energy conformer built from this compound's published connectivity and stereochemistry, paired with its verified reference values.

Drag to rotate

110 atoms

CONH

110 atoms, 112 bonds, C33H57N11O9. Connectivity and stereochemistry from PubChem CID 11765600. The arrangement is one computed low-energy conformer, not a measured structure — a flexible peptide adopts many conformations in solution.

C33H57N11O9

Molecular formula
C33H57N11O9
Molecular weight
751.88 g/mol
Sequence length
7 residues
CAS / ID
129954-34-3
Physical form
Lyophilized powder
Documented purity
Quantified by HPLC, reported per lot

Third-party verified

Independently tested, lot by lot.

Every batch of Selank is sent to an accredited independent laboratory before it ships. Here is what we screen for.

HPLC purity analysis

Quantifies purity and reports it on the lot certificate

Mass spectrometry

Verifies the exact molecular identity

Heavy metals screening

Lead, arsenic, cadmium & mercury

Endotoxins (LAL)

Bacterial endotoxin levels

Sterility testing

No microbial contamination

Net peptide content

Actual peptide mass per vial verified

FAQ

Common questions about Selank

What is Selank?

+

Selank is a seven-residue peptide built on tuftsin, a naturally occurring immune peptide, with the same stabilising tripeptide tail used in Semax. Research examines anxiolytic and stress-response endpoints, and much of the primary work sits alongside Semax in the same Russian research literature.

What is Selank researched for?

+

Published research on Selank concentrates on Anxiolytic Mechanisms, Memory & Learning, Cytokine & Immune Modulation and Transcriptomic Studies. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.

How does Selank work?

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The literature describes Selank acting across GABA-A Receptor Modulation, BDNF & Enkephalin Upregulation and Tuftsin-Derived Immune Regulation, reported respectively as GABAergic, Neurotrophin and Immunomodulatory. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.

What are the molecular specifications for Selank?

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Selank has a molecular formula of C33H57N11O9, an average mass of 751.88 g/mol and the sequence H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH. It is indexed under CAS 129954-34-3. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.

How should Selank be stored and reconstituted?

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Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. Selank is water or bacteriostatic water; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.

Is Selank approved for human use?

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No. Selank is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.

Cited sources

Peer-reviewed literature

Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.

  1. [1]PubMedThe Peptide Selank Inhibits Anxiety and Cognitive Deficits (opens in a new tab)2010 · Semenova TP et al.View source →
  2. [2]PubMedThe Nootropic and Neuroprotective Properties of Selank in a Model of Neurodegeneration (opens in a new tab)2008 · Kozlovskaya MM et al.View source →
  3. [3]PubMedImmunomodulating Activity of Selank and Its Analogs in Animal Models of Immune Disorders (opens in a new tab)2012 · Zozulya AA et al.View source →
  4. [4]PubMedEffect of Selank on Gene Expression in the Hippocampus and Frontal Cortex (opens in a new tab)2009 · Inozemtseva LS et al.View source →

For research use only

Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.

Before you order

Quality Becomes RoutineMeasured. Verified. Documented.

Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.