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Routine Peptides
HPLC tested
Representative HPLCPer lot
Pinealon research vial

Cognitive & Nootropic

Pinealon

Cognitive Peptide Studies

Third-party testedCOA per lotView COA · 99.843%
$7810mg · $7.80/mg

Quantity

1

Ships from the United States with tracking · free shipping over $200

PassedSterility & Endotoxins
PassedNet Content & Purity
Research use only
Third-party tested
COA with every lot
Tracked shipping

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Certificates of analysis

The certificate for Pinealon

Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.

Authenticity

Every vial carries a code

Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.

Verify a batch →

Verified, lot by lot

Per lot
  • Independently tested

    Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.

  • A certificate for your lot

    The report that ships with your order describes the batch you received — not the product line, and not a representative sample.

  • COA-backed replacement

    If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.

  • Tracked dispatch

    Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.

🔬
20+
Published Studies
Khavinson bioregulator research
🧬
3
Amino Acids
Glu-Asp-Arg (EDR) tripeptide
🎯
4
Research Areas
Neuroprotection & Oxidative Stress · Prenatal Neuroprotection Models · Peptide–Gene Expression & more

About this compound

What Pinealon is

C15H26N6O8

Pinealon is a tripeptide from the same Soviet-era pineal research programme that produced Epithalon. Published work focuses on neuronal survival under oxidative and hypoxic stress, with cognitive endpoints measured in animal models rather than in humans.

Formula
C15H26N6O8
Molecular weight
418.4 g/mol
Form
Lyophilized powder
Sequence length
3 residues
Read the full Pinealon research monograph →

Full specification

Sequence
L-Glutamyl-L-Aspartyl-L-Arginine (EDR tripeptide)
Molecular weight
418.40 g/mol
Molecular formula
C₁₅H₂₆N₆O₈
Physical form
Lyophilized powder
Documented purity
Quantified by HPLC, reported per lot
Storage
-20°C for long-term stability
Solubility
Water-soluble

How it works

How Pinealon works

The pathways Pinealon acts on, and what each one does. Signalling described from preclinical models.

Gene-Level Bioregulation

Peptide–DNA Interaction

Described as interacting with DNA directly and altering transcription, which places it in the same short-peptide bioregulator class as Epithalon rather than among receptor ligands.

  • Proposed binding at gene promoter regions
  • Sequence-specific expression changes reported
  • Framed as an epigenetic regulator, not a receptor agonist

Reactive Oxygen Species Suppression

Oxidative Stress

Neuronal culture work reports reduced ROS accumulation under oxidative challenge — the mechanism proposed for the survival endpoints measured alongside it.

  • Dose-dependent ROS reduction in neuronal models
  • Necrotic cell death reduced under oxidative stress
  • Measured in cerebellar granule and PC12 lines

Neuroprotection & Plasticity

Neurotrophic Support

Hypoxia and oxidative-stress models measure neuron survival. Cognitive endpoints are reported in animals; the human literature is thin.

  • Studied in prenatal hyperhomocysteinemia and hypoxia
  • Neuronal resistance to oxidative stress improved
  • Cognitive-ageing endpoints measured in animals

Uses & applications

What Pinealon is researched for

The main areas under study, and the study-reported figures behind them.

NEUROSCIENCE

Neuroprotection & Oxidative Stress

ROS accumulation and neuron survival are measured together in culture under oxidative challenge.

Khavinson et al. 2011

DEVELOPMENTAL

Prenatal Neuroprotection Models

Prenatal hypoxia models measure developmental outcomes, a design specific to this compound's literature.

Arutjunyan et al. 2012

MOLECULAR BIOLOGY

Peptide–Gene Expression

Direct DNA interaction is the proposed mechanism, placing it among short-peptide bioregulators rather than receptor ligands.

Khavinson et al. 2021

NEUROPHYSIOLOGY

Hypoxia Resistance

Survival under low oxygen is the endpoint, measured in both cell culture and whole animals.

Kozina et al. 2008

What the published work measures

The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.

  • ROS Accumulation (oxidative-stress models)
  • Necrotic Cell Death
  • Cerebellar Neuron Resistance (prenatal models)
  • Cell Viability

Molecular structure

The Pinealon molecule

A computed low-energy conformer built from this compound's published connectivity and stereochemistry, paired with its verified reference values.

Drag to rotate

55 atoms

CONH

55 atoms, 54 bonds, C15H26N6O8. Connectivity and stereochemistry from PubChem CID 10273502. The arrangement is one computed low-energy conformer, not a measured structure — a flexible peptide adopts many conformations in solution.

C15H26N6O8

Molecular formula
C15H26N6O8
Molecular weight
418.4 g/mol
Sequence length
3 residues
Physical form
Lyophilized powder
Documented purity
Quantified by HPLC, reported per lot

Third-party verified

Independently tested, lot by lot.

Every batch of Pinealon is sent to an accredited independent laboratory before it ships. Here is what we screen for.

HPLC purity analysis

Quantifies purity and reports it on the lot certificate

Mass spectrometry

Verifies the exact molecular identity

Heavy metals screening

Lead, arsenic, cadmium & mercury

Endotoxins (LAL)

Bacterial endotoxin levels

Sterility testing

No microbial contamination

Net peptide content

Actual peptide mass per vial verified

FAQ

Common questions about Pinealon

What is Pinealon?

+

Pinealon is a tripeptide from the same Soviet-era pineal research programme that produced Epithalon. Published work focuses on neuronal survival under oxidative and hypoxic stress, with cognitive endpoints measured in animal models rather than in humans.

What is Pinealon researched for?

+

Published research on Pinealon concentrates on Neuroprotection & Oxidative Stress, Prenatal Neuroprotection Models, Peptide–Gene Expression and Hypoxia Resistance. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.

How does Pinealon work?

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The literature describes Pinealon acting across Gene-Level Bioregulation, Reactive Oxygen Species Suppression and Neuroprotection & Plasticity, reported respectively as Peptide–DNA Interaction, Oxidative Stress and Neurotrophic Support. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.

What are the molecular specifications for Pinealon?

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Pinealon has a molecular formula of C15H26N6O8, an average mass of 418.4 g/mol and the sequence L-Glutamyl-L-Aspartyl-L-Arginine (EDR tripeptide). It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.

How should Pinealon be stored and reconstituted?

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Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. Pinealon is water-soluble; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.

Is Pinealon approved for human use?

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No. Pinealon is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.

Cited sources

Peer-reviewed literature

Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.

  1. [1]PUBMEDPinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes (opens in a new tab)2011 · Khavinson V et al.View source →
  2. [2]PUBMEDPinealon Protects the Rat Offspring from Prenatal Hyperhomocysteinemia (opens in a new tab)2012 · Arutjunyan A et al.View source →
  3. [3]PMCEDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation (opens in a new tab)2021 · Khavinson V et al.View source →
  4. [4]JOURNALRegulatory Peptides Protect Brain Neurons from Hypoxia in Vivo (opens in a new tab)2008 · Kozina LS et al.View source →

For research use only

Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.

Before you order

Quality Becomes RoutineMeasured. Verified. Documented.

Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.