Cognitive & Nootropic
Cognitive Function Studies
Quantity
Ships from the United States with tracking · free shipping over $200
Certificates of analysis
Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.
Authenticity
Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.
Verify a batch →Independently tested
Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.
A certificate for your lot
The report that ships with your order describes the batch you received — not the product line, and not a representative sample.
COA-backed replacement
If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.
Tracked dispatch
Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.
About this compound
C37H51N9O10S
Semax is a seven-residue peptide developed at a Russian research institute. Part of its sequence derives from ACTH; the remainder is a short stabilising tail that resists enzymatic breakdown. Published work examines BDNF expression and cognitive endpoints, largely in animal models.
Full specification
How it works
The pathways Semax acts on, and what each one does. Signalling described from preclinical models.
BDNF Modulation
Animal models report BDNF rising up to 1.4-fold in specific brain regions following administration. BDNF is the growth factor most consistently linked to neuronal survival and synaptic plasticity, which is why it serves as the primary readout.
Serotonin & Dopamine Modulation
Preclinical work describes changes in serotonergic and dopaminergic signalling alongside attention and mood endpoints. The literature treats these as observed correlates rather than an established mechanism.
Ischemic Protection
Stroke models measure infarct volume, inflammatory gene expression and neuronal survival following exposure. This is the endpoint with the largest body of published work behind it.
Uses & applications
The main areas under study, and the study-reported figures behind them.
Rodent learning and memory tasks are the primary endpoints, with BDNF measured alongside as the proposed mechanism.
Ashmarin et al. 2006
Ischaemic models measure infarct volume and neuronal survival. This is the best-evidenced area for the compound.
Gusev et al. 2010
BDNF expression is measured directly in specific brain regions rather than inferred from behavioral change.
Agapova et al. 2010
Inflammatory gene expression is measured alongside the neurological endpoints, usually within the same protocols.
Agapova et al. 2011
What the published work measures
The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.
Molecular structure
A computed low-energy conformer built from this compound's published connectivity and stereochemistry, paired with its verified reference values.
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108 atoms
108 atoms, 111 bonds, C37H51N9O10S. Connectivity and stereochemistry from PubChem CID 9811102. The arrangement is one computed low-energy conformer, not a measured structure — a flexible peptide adopts many conformations in solution.
C37H51N9O10S
Third-party verified
Every batch of Semax is sent to an accredited independent laboratory before it ships. Here is what we screen for.
Quantifies purity and reports it on the lot certificate
Verifies the exact molecular identity
Lead, arsenic, cadmium & mercury
Bacterial endotoxin levels
No microbial contamination
Actual peptide mass per vial verified
FAQ
Semax is a seven-residue peptide developed at a Russian research institute. Part of its sequence derives from ACTH; the remainder is a short stabilising tail that resists enzymatic breakdown. Published work examines BDNF expression and cognitive endpoints, largely in animal models.
Published research on Semax concentrates on Memory & Learning, Stroke Recovery, BDNF & Nerve Growth and Immune Modulation. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.
The literature describes Semax acting across BDNF Modulation, Serotonin & Dopamine Modulation and Ischemic Protection, reported respectively as Neurotrophic, Neurotransmitter and Neuroprotective. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.
Semax has a molecular formula of C37H51N9O10S, an average mass of 813.93 g/mol and the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.
Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. Semax is water-soluble; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.
No. Semax is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.
Cited sources
Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.
For research use only
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
Before you order
Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.
