Regenerative & Repair
Immune Response Studies
Quantity
Ships from the United States with tracking · free shipping over $200
Certificates of analysis
Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.
Authenticity
Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.
Verify a batch →Independently tested
Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.
A certificate for your lot
The report that ships with your order describes the batch you received — not the product line, and not a representative sample.
COA-backed replacement
If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.
Tracked dispatch
Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.
About this compound
C129H215N33O55
Thymosin Alpha-1 is a 28-residue peptide first isolated from the thymus, the organ where T-cells mature. It occurs naturally as a cleavage product of a larger precursor protein, and research examines T-cell signaling and immune-response endpoints — making it one of the more clinically characterized compounds in this catalog.
Full specification
How it works
The pathways Thymosin Alpha-1 acts on, and what each one does. Signalling described from preclinical models.
Thymic Immune Modulation
First isolated from the thymus, where T-cells mature. It occurs naturally as a cleavage product of a larger precursor, and T-cell maturation remains the endpoint it is most associated with.
Toll-Like Receptor Activation
Reported to signal through TLR2 and TLR9 on dendritic cells — the innate arm — which is how a peptide characterized in adaptive immunity came to be studied on both sides.
NK & Th1 Cytokine Modulation
Natural-killer cell activity and a Th1-weighted cytokine profile are the measured outputs, making this among the more clinically characterized compounds in the catalog.
Uses & applications
The main areas under study, and the study-reported figures behind them.
T-cell maturation is the endpoint the peptide is most associated with, following from its isolation from the thymus.
Garaci et al. 2007
Antiviral endpoints are measured through immune activation rather than through any direct action on the virus.
Loggi et al. 2020
Tumour models measure immune-mediated response, an application that follows from the same T-cell mechanism.
Costantini et al. 2019
A Th1-weighted cytokine profile is the measured output, alongside natural-killer cell activity.
Romani et al. 2012
What the published work measures
The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.
Molecular structure
The verified reference values for this compound.
No 3D structure published
This compound is a long, flexible chain. Any single three-dimensional arrangement would be one of an enormous number it can adopt, so we do not show one. The sequence and the reference values beside this are the reliable description.
C129H215N33O55
Third-party verified
Every batch of Thymosin Alpha-1 is sent to an accredited independent laboratory before it ships. Here is what we screen for.
Quantifies purity and reports it on the lot certificate
Verifies the exact molecular identity
Lead, arsenic, cadmium & mercury
Bacterial endotoxin levels
No microbial contamination
Actual peptide mass per vial verified
FAQ
Thymosin Alpha-1 is a 28-residue peptide first isolated from the thymus, the organ where T-cells mature. It occurs naturally as a cleavage product of a larger precursor protein, and research examines T-cell signaling and immune-response endpoints — making it one of the more clinically characterized compounds in this catalog.
Published research on Thymosin Alpha-1 concentrates on T-Cell Research, Viral-Response Models, Tumour-Immunity Models and Cytokine Regulation. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.
The literature describes Thymosin Alpha-1 acting across Thymic Immune Modulation, Toll-Like Receptor Activation and NK & Th1 Cytokine Modulation, reported respectively as T-Cell Maturation, TLR Signaling and Cytokine / NK. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.
Thymosin Alpha-1 has a molecular formula of C129H215N33O55 and an average mass of 3108.29 g/mol. It is indexed under CAS 62304-98-7. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.
Store the sealed vial at Store at -20°C, protected from light, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.
No. Thymosin Alpha-1 is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.
Cited sources
Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.
For research use only
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
Before you order
Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.
