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Routine Peptides
HPLC tested
Representative HPLCPer lot
Tesamorelin research vial

Growth Hormone

Tesamorelin

Growth Hormone Release Studies

Third-party testedCOA per lotView COA · 99.33%
$12610mg · $12.60/mg

Quantity

1

Ships from the United States with tracking · free shipping over $200

PassedSterility & Endotoxins
PassedNet Content & Purity
Research use only
Third-party tested
COA with every lot
Tracked shipping

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Authenticity

Every vial carries a code

Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.

Verify a batch →

Verified, lot by lot

Per lot
  • Independently tested

    Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.

  • A certificate for your lot

    The report that ships with your order describes the batch you received — not the product line, and not a representative sample.

  • COA-backed replacement

    If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.

  • Tracked dispatch

    Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.

🔬
50+
Published Studies
GHRH analog research papers
🧬
44
Amino Acids
Full-length GHRH(1-44) analog
⚗️
2010
FDA Approval (Egrifta)
HIV-associated lipodystrophy
🎯
4
Research Areas
Visceral Fat & Body Composition · Brain Structure & Function · GH/IGF-1 Axis & more

About this compound

What Tesamorelin is

C221H366N72O67S

Tesamorelin is a synthetic GHRH matching the full 44-residue human sequence, with a trans-3-hexenoyl group added at the N-terminus to resist enzymatic degradation. Unlike shorter GHRH fragments, it preserves the complete native sequence, and research examines growth hormone release and visceral adipose endpoints.

Formula
C221H366N72O67S
Molecular weight
5135.89 g/mol
Form
Lyophilized Powder
CAS / ID
218949-48-5
Read the full Tesamorelin research monograph →

Full specification

Sequence
Modified GHRH(1-44) analog (44 amino acids)
Molecular weight
5,135.80 g/mol
Molecular formula
C₂₂₁H₃₆₆N₇₂O₆₇S
Physical form
Lyophilized powder
Documented purity
Quantified by HPLC, reported per lot
Storage
-20°C for long-term stability
Solubility
Water-soluble

How it works

How Tesamorelin works

The pathways Tesamorelin acts on, and what each one does. Signalling described from preclinical models.

Growth Hormone Secretagogue

GHRH-R Agonism

A synthetic GHRH matching the full 44-residue human sequence, with a trans-3-hexenoyl group at the N-terminus to resist degradation. Unlike shorter fragments it preserves the complete native sequence.

  • Selective for the GHRH receptor
  • Pulsatile secretion physiology preserved
  • IGF-1 production follows downstream

Visceral Adipose Reduction

Lipolysis

Visceral adipose tissue is the endpoint with the largest clinical dataset behind this compound, and the one that distinguishes it from other GHRH analogues in the literature.

  • Hormone-sensitive lipase activity raised
  • Visceral rather than subcutaneous fat targeted
  • Lean mass preserved in research models

Cognitive & Brain Research

Neuroprotection

A smaller body of work examines cognitive endpoints on the basis that growth hormone signalling reaches the central nervous system. Findings here are preliminary relative to the adipose data.

  • Circulating IGF-1 crosses the blood-brain barrier
  • Cortical gray matter volume changes reported
  • Cognitive-ageing models under investigation

Uses & applications

What Tesamorelin is researched for

The main areas under study, and the study-reported figures behind them.

Metabolic

Visceral Fat & Body Composition

Visceral adipose tissue carries the largest clinical dataset for this compound and distinguishes it from other GHRH analogues.

Falutz et al. 2010

Cognitive Research

Brain Structure & Function

Cognitive and imaging endpoints are examined on the basis that growth hormone signalling reaches the central nervous system.

Baker et al. 2019

Endocrinology

GH/IGF-1 Axis

IGF-1 is measured as the downstream marker of release, as with every compound acting upstream of the pituitary.

Stanley et al. 2011

Cardiometabolic

Lipid & Cardiovascular Markers

Lipid profiles are tracked alongside body composition, since the two move together in this literature.

Falutz et al. 2014

What the published work measures

The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.

  • Visceral Adipose Tissue Reduction (Phase III)
  • IGF-1 Level Increase
  • Trunk Fat Area Reduction
  • Lean Body Mass Preservation

Molecular structure

The Tesamorelin molecule

The verified reference values for this compound.

No 3D structure published

This compound is a long, flexible chain. Any single three-dimensional arrangement would be one of an enormous number it can adopt, so we do not show one. The sequence and the reference values beside this are the reliable description.

C221H366N72O67S

Molecular formula
C221H366N72O67S
Molecular weight
5135.89 g/mol
Sequence length
44 residues
CAS / ID
218949-48-5
Physical form
Lyophilized Powder
Documented purity
Quantified by HPLC, reported per lot

Third-party verified

Independently tested, lot by lot.

Every batch of Tesamorelin is sent to an accredited independent laboratory before it ships. Here is what we screen for.

HPLC purity analysis

Quantifies purity and reports it on the lot certificate

Mass spectrometry

Verifies the exact molecular identity

Heavy metals screening

Lead, arsenic, cadmium & mercury

Endotoxins (LAL)

Bacterial endotoxin levels

Sterility testing

No microbial contamination

Net peptide content

Actual peptide mass per vial verified

FAQ

Common questions about Tesamorelin

What is Tesamorelin?

+

Tesamorelin is a synthetic GHRH matching the full 44-residue human sequence, with a trans-3-hexenoyl group added at the N-terminus to resist enzymatic degradation. Unlike shorter GHRH fragments, it preserves the complete native sequence, and research examines growth hormone release and visceral adipose endpoints.

What is Tesamorelin researched for?

+

Published research on Tesamorelin concentrates on Visceral Fat & Body Composition, Brain Structure & Function, GH/IGF-1 Axis and Lipid & Cardiovascular Markers. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.

How does Tesamorelin work?

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The literature describes Tesamorelin acting across Growth Hormone Secretagogue, Visceral Adipose Reduction and Cognitive & Brain Research, reported respectively as GHRH-R Agonism, Lipolysis and Neuroprotection. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.

What are the molecular specifications for Tesamorelin?

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Tesamorelin has a molecular formula of C221H366N72O67S, an average mass of 5135.89 g/mol and the sequence Modified GHRH(1-44) analog (44 amino acids). It is indexed under CAS 218949-48-5. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.

How should Tesamorelin be stored and reconstituted?

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Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. Tesamorelin is water-soluble; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.

Is Tesamorelin approved for human use?

+

No. Tesamorelin is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.

Cited sources

Peer-reviewed literature

Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.

  1. [1]PubMedEffects of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients with Abdominal Fat Accumulation (opens in a new tab)Falutz J et al. — 2010View source →
  2. [2]PubMedEffects of Growth Hormone–Releasing Hormone on Cognitive Function in Adults with Mild Cognitive Impairment and Healthy Adults (opens in a new tab)Baker LD et al. — 2019View source →
  3. [3]PubMedTesamorelin, a Growth Hormone–Releasing Factor Analogue, Reduces Carotid Intima Media Thickness in HIV-Infected Patients (opens in a new tab)Falutz J et al. — 2014View source →
  4. [4]PubMedTesamorelin: A Synthetic Growth Hormone-Releasing Factor Analogue for HIV-Associated Lipodystrophy (opens in a new tab)Stanley TL et al. — 2011View source →

For research use only

Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.

Before you order

Quality Becomes RoutineMeasured. Verified. Documented.

Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.