Growth Hormone
GH Pulse Studies
Quantity
Ships from the United States with tracking · free shipping over $200
Certificates of analysis
Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.
Authenticity
Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.
Verify a batch →Independently tested
Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.
A certificate for your lot
The report that ships with your order describes the batch you received — not the product line, and not a representative sample.
COA-backed replacement
If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.
Tracked dispatch
Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.
About this compound
C38H49N9O5
Ipamorelin is a five-residue peptide binding GHS-R, the growth hormone secretagogue receptor. It is studied specifically for its selectivity: unlike earlier secretagogues, published work reports minimal effect on cortisol and prolactin at comparable doses, which is why it appears so often in growth-hormone pulse research.
Full specification
How it works
The pathways Ipamorelin acts on, and what each one does. Signalling described from preclinical models.
Ghrelin Receptor Activation
Binding is selective for GHSR-1a on anterior pituitary somatotrophs, which is the receptor population that releases growth hormone. Selectivity at that site is the compound's defining property.
No Cortisol or Prolactin Elevation
At doses producing substantial growth hormone release, published work reports no meaningful rise in ACTH, cortisol or prolactin — the off-target effects that limited earlier secretagogues in the same class.
Physiologic GH Secretion Pattern
Release occurs in discrete bursts rather than as a sustained elevation, matching the pattern of endogenous secretion. Whether pulse shape matters as much as total exposure is an open question the literature keeps returning to.
Uses & applications
The main areas under study, and the study-reported figures behind them.
Selectivity is the property under study: growth hormone release without the cortisol and prolactin rise earlier secretagogues produced.
Raun et al. 1998
Endogenous release peaks during slow-wave sleep, so sleep-phase dosing is a recurring variable in the protocols.
Frieboes et al. 2004
Bone mineral density and longitudinal growth are measured in rodent models as downstream consequences of altered release.
Raun et al. 1998
Combination work tests whether engaging the ghrelin and GHRH receptors together amplifies the pulse beyond either alone.
Raun et al. 1998
What the published work measures
The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.
Molecular structure
A computed low-energy conformer built from this compound's published connectivity and stereochemistry, paired with its verified reference values.
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101 atoms
101 atoms, 104 bonds, C38H49N9O5. Connectivity and stereochemistry from PubChem CID 9831659. The arrangement is one computed low-energy conformer, not a measured structure — a flexible peptide adopts many conformations in solution.
C38H49N9O5
Third-party verified
Every batch of Ipamorelin is sent to an accredited independent laboratory before it ships. Here is what we screen for.
Quantifies purity and reports it on the lot certificate
Verifies the exact molecular identity
Lead, arsenic, cadmium & mercury
Bacterial endotoxin levels
No microbial contamination
Actual peptide mass per vial verified
FAQ
Ipamorelin is a five-residue peptide binding GHS-R, the growth hormone secretagogue receptor. It is studied specifically for its selectivity: unlike earlier secretagogues, published work reports minimal effect on cortisol and prolactin at comparable doses, which is why it appears so often in growth-hormone pulse research.
Published research on Ipamorelin concentrates on Selective GH Secretagogue, GH Secretion & Sleep, Bone Growth Models and Synergy with GHRH Analogs. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.
The literature describes Ipamorelin acting across Ghrelin Receptor Activation, No Cortisol or Prolactin Elevation and Physiologic GH Secretion Pattern, reported respectively as GHSR-1a Agonist, Selectivity and Pulsatile GH. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.
Ipamorelin has a molecular formula of C38H49N9O5, an average mass of 711.85 g/mol and the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. It is indexed under CAS 170851-70-4. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.
Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. Ipamorelin is water-soluble; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.
No. Ipamorelin is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.
Cited sources
Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.
For research use only
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
Before you order
Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.
