Growth Hormone
GH Half-Life Studies
Quantity
Ships from the United States with tracking · free shipping over $200
Certificates of analysis
Each certificate covers one production run, and reports on that batch alone. Open any of them to read the laboratory report exactly as the third-party lab issued it.
Authenticity
Scan the code on the label to pull up every published certificate for that compound — the same reports the third-party laboratory issued, batch by batch. Traceable from the laboratory that tested it to your bench.
Verify a batch →Independently tested
Purity is quantified by reverse-phase HPLC and identity confirmed by mass spectrometry, by an outside laboratory rather than in-house.
A certificate for your lot
The report that ships with your order describes the batch you received — not the product line, and not a representative sample.
COA-backed replacement
If material does not match the certificate issued for its lot, we replace it or refund it. Send us the lot number and we will trace it.
Tracked dispatch
Tracking is issued when the label is created, so the shipment is traceable from the moment it leaves us.
About this compound
C152H252N44O42
CJC-1295 without DAC is a modified GHRH fragment carrying four amino acid substitutions. Each substitution targets a site where enzymes would otherwise cleave the sequence, extending how long the molecule survives in circulation compared with unmodified GHRH. Research measures growth hormone release profiles and the shape of the resulting pulse.
Full specification
How it works
The pathways CJC-1295 acts on, and what each one does. Signalling described from preclinical models.
GHRH Receptor Activation
Four substitutions — at positions 2, 8, 15 and 27 — each block a site where enzymes would cleave native GHRH(1-29). The receptor interaction is unchanged; only the molecule's survival time is.
Pulsatile GH Secretion
A roughly thirty-minute half-life produces discrete pulses rather than the sustained elevation the DAC variant gives. That difference is the reason both versions exist and are studied separately.
GH/IGF-1 Axis Stimulation
Each pulse drives a transient rise in hepatic IGF-1. Because exposure is brief, the IGF-1 profile differs markedly from the prolonged elevation reported with the DAC variant.
Uses & applications
The main areas under study, and the study-reported figures behind them.
The short half-life is the feature here: it produces discrete pulses, which is what makes the compound useful for studying release pattern rather than total exposure.
Teichman et al. 2006
Most often studied head-to-head against the DAC variant, where the only meaningful variable is duration of action.
Frohman et al. 2003
Combination work pairs it with a ghrelin-receptor agonist to test whether engaging two receptor populations amplifies the pulse.
Raun et al. 1998
Animal models examine whether upstream stimulation restores a release pattern closer to normal physiology than exogenous growth hormone does.
Alba et al. 2006
What the published work measures
The endpoints reported across the literature for this compound. The figures belong to the individual papers, not to us.
Molecular structure
The verified reference values for this compound.
No 3D structure published
This compound is a long, flexible chain. Any single three-dimensional arrangement would be one of an enormous number it can adopt, so we do not show one. The sequence and the reference values beside this are the reliable description.
C152H252N44O42
Third-party verified
Every batch of CJC-1295 is sent to an accredited independent laboratory before it ships. Here is what we screen for.
Quantifies purity and reports it on the lot certificate
Verifies the exact molecular identity
Lead, arsenic, cadmium & mercury
Bacterial endotoxin levels
No microbial contamination
Actual peptide mass per vial verified
FAQ
CJC-1295 without DAC is a modified GHRH fragment carrying four amino acid substitutions. Each substitution targets a site where enzymes would otherwise cleave the sequence, extending how long the molecule survives in circulation compared with unmodified GHRH. Research measures growth hormone release profiles and the shape of the resulting pulse.
Published research on CJC-1295 concentrates on Pulsatile GH Research, GHRH Analog Comparison, CJC / Ipamorelin Synergy and GHRH Axis Restoration. Each of those areas is summarised further up this page with the citation it comes from, and the full reference list — 4 indexed publications — sits at the bottom. Study designs and concentrations vary considerably between publications, so the primary sources are worth reading directly.
The literature describes CJC-1295 acting across GHRH Receptor Activation, Pulsatile GH Secretion and GH/IGF-1 Axis Stimulation, reported respectively as GHRH-R Agonist, Pulsatile GH and IGF-1 Axis. Those pathways are drawn from preclinical models rather than clinical work, and they describe what has been observed rather than a settled mechanism — the individual pathway cards above cite what each one is based on.
CJC-1295 has a molecular formula of C152H252N44O42 and an average mass of 3367.97 g/mol. It is indexed under CAS 863288-34-0. It ships as lyophilized powder. Those are nominal reference values for the parent compound. The identity of the specific material you receive is confirmed by mass spectrometry and reported on that lot's certificate.
Store the sealed vial at -20°C, protected from light and moisture, and let it reach room temperature before opening so condensation does not form on cold powder. CJC-1295 is water-soluble; reconstitute by directing the diluent down the vial wall rather than onto the powder, then swirl to dissolve rather than shaking. Keep reconstituted solution refrigerated and avoid repeated freeze-thaw cycles — solutions are far less stable than lyophilized powder.
No. CJC-1295 is supplied strictly for in-vitro laboratory research and development. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and it is not intended for human or animal consumption, ingestion, injection or any in-vivo use. Ordering confirms you are a qualified researcher or institution purchasing on that basis.
Cited sources
Independent published research indexed from PubMed and peer-reviewed journals — not Routine Peptides claims.
For research use only
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
Before you order
Every production run is analyzed by an independent laboratory, and the certificate for your lot travels with the order — not a catalog-wide document, and not a summary written by us.
